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B020883 - ELEMENTS OF NEUROLOGY AND COGNITIVE REHABILITATION
Main information
Teaching Language
Suggested readings
Learning Objectives
Teaching Methods
Type of Assessment
Course program
Academic Year 2018-19
Course year
First year - Second Semester
Belonging Department
Health Sciences (DSS)
Course Type
Single education field course
Scientific Area
MED/26 - NEUROLOGY
Credits
6
Teaching Hours
42
Teaching Term
04/03/2019 ⇒ 31/05/2019
Attendance required
No
Type of Evaluation
Final Grade
Course program
show
Lectureship
Teaching Language
Italian
Suggested readings (Search our library's catalogue)
A Neurology handbook is suggested to deepen the topics of the lessons.
Below some suggested papers:
Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., ... & Snyder, P. J. (2011). The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 270-279.
Jack, C. R., Albert, M. S., Knopman, D. S., McKhann, G. M., Sperling, R. A., Carrillo, M. C., ... & Phelps, C. H. (2011). Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 257-262.
Jack, C. R. J., Bennett, D. A., Blennow, K., Carrillo, M. C., Dunn, B., & Elliott, C. (2017). NIA-AA research framework: towards a biological definition of Alzheimer’s disease.
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., ... & Mohs, R. C. (2011). The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 263-269.
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., ... & Park, D. C. (2011). Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 280-292.
Piguet, O., Hornberger, M., Mioshi, E., & Hodges, J. R. (2011). Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management. The Lancet Neurology, 10(2), 162-172.
Rascovsky, K., Hodges, J. R., Kipps, C. M., Johnson, J. K., Seeley, W. W., Mendez, M. F., ... & Galasko, D. (2007). Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Disease & Associated Disorders, 21(4), S14-S18.
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., ... & Hillis, A. E. (2011). Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain, 134(9), 2456-2477.
Caballol, N., Martí, M. J., & Tolosa, E. (2007). Cognitive dysfunction and dementia in Parkinson disease. Movement Disorders, 22(S17).
Litvan, I., Goldman, J. G., Tröster, A. I., Schmand, B. A., Weintraub, D., Petersen, R. C., ... & Aarsland, D. (2012). Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Movement disorders, 27(3), 349-356.
Litvan, I., Aarsland, D., Adler, C. H., Goldman, J. G., Kulisevsky, J., Mollenhauer, B., ... & Weintraub, D. (2011). MDS task force on mild cognitive impairment in Parkinson's disease: Critical review of PD‐MCI. Movement disorders, 26(10), 1814-1824.
Bouwman, F., Orini, S., Gandolfo, F., Altomare, D., Festari, C., Agosta, F., ... & Walker, Z. (2018). Diagnostic utility of FDG-PET in the differential diagnosis between different forms of primary progressive aphasia. European journal of nuclear medicine and molecular imaging, 1-8.
Catricalà, E., Gobbi, E., Battista, P., Miozzo, A., Polito, C., Boschi, V., ... & Cappa, S. F. (2017). SAND: a Screening for Aphasia in NeuroDegeneration. Development and normative data. Neurological Sciences, 38(8), 1469-1483.
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. E. E. A., ... & Manes, F. (2011). Classification of primary progressive aphasia and its variants. Neurology, 76(11), 1006-1014.
Grossman, M. (2018). Linguistic aspects of primary progressive aphasia. Annual Review of Linguistics, (0).
Woods B, Aguirre E, Spector AE, Orrell M. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database Syst Rev. 2012 Feb 15;2:CD005562. doi: 10.1002/14651858.CD005562.pub2. Review.
Bahar-Fuchs A, Clare L, Woods B. Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev. 2013 Jun 5;6:CD003260. doi:
10.1002/14651858.CD003260.pub2. Review.
Gillespie DC, Bowen A, Chung CS, Cockburn J, Knapp P, Pollock A. Rehabilitation for post-stroke cognitive impairment: an overview of recommendations arising from systematic reviews of current evidence. Clin Rehabil. 2015 Feb;29(2):120-8. doi: 10.1177/0269215514538982.
Robertson IH, Murre JM. Rehabilitation of brain damage: brain plasticity and principles of guided recovery. Psychol Bull. 1999 Sep;125(5):544-75. Review.
O'Brien JT, Erkinjuntti T, Reisberg B, Roman G, Sawada T, Pantoni L, Bowler JV, Ballard C, DeCarli C, Gorelick PB, Rockwood K, Burns A, Gauthier S, DeKosky ST. Vascular cognitive impairment. Lancet Neurol. 2003 Feb;2(2):89-98. Review.
Below some suggested papers:
Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., ... & Snyder, P. J. (2011). The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 270-279.
Jack, C. R., Albert, M. S., Knopman, D. S., McKhann, G. M., Sperling, R. A., Carrillo, M. C., ... & Phelps, C. H. (2011). Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 257-262.
Jack, C. R. J., Bennett, D. A., Blennow, K., Carrillo, M. C., Dunn, B., & Elliott, C. (2017). NIA-AA research framework: towards a biological definition of Alzheimer’s disease.
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., ... & Mohs, R. C. (2011). The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 263-269.
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., ... & Park, D. C. (2011). Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 280-292.
Piguet, O., Hornberger, M., Mioshi, E., & Hodges, J. R. (2011). Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management. The Lancet Neurology, 10(2), 162-172.
Rascovsky, K., Hodges, J. R., Kipps, C. M., Johnson, J. K., Seeley, W. W., Mendez, M. F., ... & Galasko, D. (2007). Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Disease & Associated Disorders, 21(4), S14-S18.
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., ... & Hillis, A. E. (2011). Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain, 134(9), 2456-2477.
Caballol, N., Martí, M. J., & Tolosa, E. (2007). Cognitive dysfunction and dementia in Parkinson disease. Movement Disorders, 22(S17).
Litvan, I., Goldman, J. G., Tröster, A. I., Schmand, B. A., Weintraub, D., Petersen, R. C., ... & Aarsland, D. (2012). Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Movement disorders, 27(3), 349-356.
Litvan, I., Aarsland, D., Adler, C. H., Goldman, J. G., Kulisevsky, J., Mollenhauer, B., ... & Weintraub, D. (2011). MDS task force on mild cognitive impairment in Parkinson's disease: Critical review of PD‐MCI. Movement disorders, 26(10), 1814-1824.
Bouwman, F., Orini, S., Gandolfo, F., Altomare, D., Festari, C., Agosta, F., ... & Walker, Z. (2018). Diagnostic utility of FDG-PET in the differential diagnosis between different forms of primary progressive aphasia. European journal of nuclear medicine and molecular imaging, 1-8.
Catricalà, E., Gobbi, E., Battista, P., Miozzo, A., Polito, C., Boschi, V., ... & Cappa, S. F. (2017). SAND: a Screening for Aphasia in NeuroDegeneration. Development and normative data. Neurological Sciences, 38(8), 1469-1483.
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. E. E. A., ... & Manes, F. (2011). Classification of primary progressive aphasia and its variants. Neurology, 76(11), 1006-1014.
Grossman, M. (2018). Linguistic aspects of primary progressive aphasia. Annual Review of Linguistics, (0).
Woods B, Aguirre E, Spector AE, Orrell M. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database Syst Rev. 2012 Feb 15;2:CD005562. doi: 10.1002/14651858.CD005562.pub2. Review.
Bahar-Fuchs A, Clare L, Woods B. Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev. 2013 Jun 5;6:CD003260. doi:
10.1002/14651858.CD003260.pub2. Review.
Gillespie DC, Bowen A, Chung CS, Cockburn J, Knapp P, Pollock A. Rehabilitation for post-stroke cognitive impairment: an overview of recommendations arising from systematic reviews of current evidence. Clin Rehabil. 2015 Feb;29(2):120-8. doi: 10.1177/0269215514538982.
Robertson IH, Murre JM. Rehabilitation of brain damage: brain plasticity and principles of guided recovery. Psychol Bull. 1999 Sep;125(5):544-75. Review.
O'Brien JT, Erkinjuntti T, Reisberg B, Roman G, Sawada T, Pantoni L, Bowler JV, Ballard C, DeCarli C, Gorelick PB, Rockwood K, Burns A, Gauthier S, DeKosky ST. Vascular cognitive impairment. Lancet Neurol. 2003 Feb;2(2):89-98. Review.
Learning Objectives
Provide general knowledge about clinical neurology, more specifically: principal neurological syndromes, diagnostic algorithms and rationale of therapeutic interventions in the nervous system diseases, with particular attention to neurocognitive rehabilitation.
Teaching Methods
Frontal lessons
Type of Assessment
Oral exam
Course program
Elements of functional neuroanatomy. Assessment of the neurological patient e principles of neurological semiology (symptomatology, functional, motor, cognitive and psychiatric disturbances). Instrumental and laboratory exams, and differential diagnosis. Impairment of cognitive functions (elements of neuropsychology, dementia diagnostic criteria and principals clinical presentations, Alzheimer's disease, Parkinson's disease, Frontotemporal dementia, primary progressive aphasias). Definition of the principal types of cognitive decline and dementia: neurodegenerative and cerebrovascular syndromes. Cognitive rehabilitation: definition, principles and rationale of rehabilitative approaches for cognitive impairment. Neuroscientific bases of cognitive rehabilitation: neuronal plasticity. Cognitive rehabilitation for dementias.