Si consiglia di avvalersi di un manuale di Neurologia per approfondire gli argomenti trattati durante le lezioni frontali.
A seguire alcuni articoli consigliati:
Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., ... & Snyder, P. J. (2011). The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 270-279.
Jack, C. R., Albert, M. S., Knopman, D. S., McKhann, G. M., Sperling, R. A., Carrillo, M. C., ... & Phelps, C. H. (2011). Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 257-262.
Jack, C. R. J., Bennett, D. A., Blennow, K., Carrillo, M. C., Dunn, B., & Elliott, C. (2017). NIA-AA research framework: towards a biological definition of Alzheimer’s disease.
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., ... & Mohs, R. C. (2011). The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 263-269.
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., ... & Park, D. C. (2011). Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & dementia: the journal of the Alzheimer's Association, 7(3), 280-292.
Piguet, O., Hornberger, M., Mioshi, E., & Hodges, J. R. (2011). Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management. The Lancet Neurology, 10(2), 162-172.
Rascovsky, K., Hodges, J. R., Kipps, C. M., Johnson, J. K., Seeley, W. W., Mendez, M. F., ... & Galasko, D. (2007). Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Disease & Associated Disorders, 21(4), S14-S18.
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., ... & Hillis, A. E. (2011). Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain, 134(9), 2456-2477.
Caballol, N., Martí, M. J., & Tolosa, E. (2007). Cognitive dysfunction and dementia in Parkinson disease. Movement Disorders, 22(S17).
Litvan, I., Goldman, J. G., Tröster, A. I., Schmand, B. A., Weintraub, D., Petersen, R. C., ... & Aarsland, D. (2012). Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Movement disorders, 27(3), 349-356.
Litvan, I., Aarsland, D., Adler, C. H., Goldman, J. G., Kulisevsky, J., Mollenhauer, B., ... & Weintraub, D. (2011). MDS task force on mild cognitive impairment in Parkinson's disease: Critical review of PD‐MCI. Movement disorders, 26(10), 1814-1824.
Bouwman, F., Orini, S., Gandolfo, F., Altomare, D., Festari, C., Agosta, F., ... & Walker, Z. (2018). Diagnostic utility of FDG-PET in the differential diagnosis between different forms of primary progressive aphasia. European journal of nuclear medicine and molecular imaging, 1-8.
Catricalà, E., Gobbi, E., Battista, P., Miozzo, A., Polito, C., Boschi, V., ... & Cappa, S. F. (2017). SAND: a Screening for Aphasia in NeuroDegeneration. Development and normative data. Neurological Sciences, 38(8), 1469-1483.
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. E. E. A., ... & Manes, F. (2011). Classification of primary progressive aphasia and its variants. Neurology, 76(11), 1006-1014.
Grossman, M. (2018). Linguistic aspects of primary progressive aphasia. Annual Review of Linguistics, (0).
Woods B, Aguirre E, Spector AE, Orrell M. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database Syst Rev. 2012 Feb 15;2:CD005562. doi: 10.1002/14651858.CD005562.pub2. Review.
Bahar-Fuchs A, Clare L, Woods B. Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev. 2013 Jun 5;6:CD003260. doi:
10.1002/14651858.CD003260.pub2. Review.
Gillespie DC, Bowen A, Chung CS, Cockburn J, Knapp P, Pollock A. Rehabilitation for post-stroke cognitive impairment: an overview of recommendations arising from systematic reviews of current evidence. Clin Rehabil. 2015 Feb;29(2):120-8. doi: 10.1177/0269215514538982.
Robertson IH, Murre JM. Rehabilitation of brain damage: brain plasticity and principles of guided recovery. Psychol Bull. 1999 Sep;125(5):544-75. Review.
Fornire conoscenze di base di neurologia clinica che permettano al
discente di orientarsi sulle principali sindromi neurologiche e di
comprendere gli iter diagnostici ed il razionale degli interventi terapeutici
nelle malattie del sistema nervoso, con particolare attenzione agli aspetti
neuroriabilitativi.
Metodi Didattici
Didattica frontale
Modalità di verifica apprendimento
Esame orale
Programma del corso
Elementi di neuroanatomia funzionale
Valutazione del paziente neurologico e principi di semeiotica neurologica (sintomatologia, alterazioni funzionali, motorie, cognitive, psichiatriche)
Indagini strumentali e di laboratorio, e diagnosi differenziale
Disturbi delle funzioni cognitive (elementi di neuropsicologia, criteri diagnostici per la demenza e principali quadri clinici, malattia di Alzheimer, malattia di Parkinson, Demenza Frontotemporale, Afasie primarie progressive)
Inquadramento delle principali forme di deterioramento cognitivo e demenza:
• Patologie neurodegenerative
• Patologie cerebrovascolari
La riabilitazione cognitiva: definizioni, principi e razionale degli approcci riabilitativi ai disturbi neuropsicologici
Basi neuroscientifiche della riabilitazione cognitiva: la plasticità neuronale
La riabilitazione cognitiva nelle demenze